Morphological and radiological study of lymph nodes in dromedaries in Algeria

Keywords: anatomy; topography; dromedary; morphometric parameters; radiology; contrast agent.


Despite significant progress in the study of the subtle mechanisms of interaction between cellular and molecular elements in immune responses, the general structure of the organs of the immune system, including the lymph node, has not been sufficiently studied, in particular in large farm animals. The lymph nodes of sexually mature camels have been studied anatomically and morphologically and advanced studies conducted using an X-ray system and a computer densitometer scanner with injection of a contrast medium. The topography and characteristics of the morphometric parameters (absolute and relative mass, linear measurements, volume) of certain somatic and visceral lymph nodes were determined. The mass of the lymph nodes studied varies according to the location and the interest of the organ in the satellite defense of the lymphoid system, For part of the x-ray examination of the lymph nodes, organs of large inguinal and axillary shape were selected after passing through a solution of tetraethyl-4,4-diamino-triphenylmethane oxalate, the lymph vessels were dilated and darkened, then iodine injections were made into the afferent lymphatic vessel of two lymph nodes; they were placed on the radiological cassette, a photograph taken on conventional radiography, for computer densitometer, the examination was made without preparation of the organs. A capsule encompasses the parenchyma of the lymph node, whose internal structure is composed of different zones, cortical, paracortical and medullary, on the one hand the lymphatic vessels were very clear especially with the conventional radiography with preparation of the organs, while the computer densitometer clearly revealed the deep texture of the parenchyma, basing it on the intensity of emission saturation from the use of computer densitometer.


Abdel-Magied, E. M., Taha, A. A. M., Al-Qarawi, A. A., & Elfaki, M. G. (2001). The parotid, mandibular and lateral retropharyngeal lymph nodes of the camel (Camelus dromedarius). Anatomia, Histologia, Embryologia: Journal of Veterinary Medicine Series C, 30(4), 199–203.

Al Aiyan, A., Abdullah, S., Menon, P., Shawaf, T., Al Darwich, A., & Barigye, R. (2019). A histologic and histomorphometric study of the second stomach chamber of the dromedary (Camelus dromedarius). Journal of Camel Practice and Research, 26(1), 91.

Artemeva, E., & Chekarova, I. (2019). Varieties of atypical lymph nodes of water deer (Hydropotes inermis argyropus). IOP Conference Series: Earth and Environmental Science, 403, 012149.

Ashwini, S., Pawar, A. A., Sathisha, K. K., & Girish, M. H. (2018). Light and electron microscopic study of lungs in Bidri goat and Deccani sheep. The Indian Journal of Veterinary Sciences and Biotechnology, 13(3), 10601.

Bodi, I., H.-Minko, K., Prodan, Z., & Olah, I. (2020). Compartmentalization of human thymic medulla: facts and hypotheses. Thymus. 145–240.

Davenport, M. S., Perazella, M. A., Yee, J., Dillman, J. R., Fine, D., McDonald, R. J., Rodby, R. A., Wang, C. L., & Weinreb, J. C. (2020). Use of intravenous iodinated contrast media in patients with kidney disease. Kidney Medicine, 2(1), 85–93.

Elmore, S. A. (2006). Histopathology of the lymph nodes. Toxicologic Pathology, 34(5), 425–454.

Fowler, M. E., Smuts, M. M. S., & Bezuidenhout, A. J. (1988). Anatomy of the dromedary. The Journal of Zoo Animal Medicine, 19(3), 136.

Gadre, K. M., Ashok, P., Arun, K., & Mukartal, S. Y. (2018). Comparitive morphometry and histomorphological study on superficial lymph nodes of forelimb and hindlimb in Deccani sheep (Ovies aries) and Bidri goat (Capra hircus). Journal of Experimental Zoology, India, 21(2), 1159–1161.

Gasisova, A. I., Atkenova, A. B., Ahmetzhanova, N. B., Murzabekova, L. M., & Bekenova, A. C. (2016). Morphostructure of immune system organs in cattle of different age. Anatomia, Histologia, Embryologia, 46(2), 132–142.

Gavrilin, P. M., & Kolesnyk, A. O. (2019). Lymphatic supply and architectonics of intranodal lymphatic channel of lymph nodes of domestic pig. Theoretical and Applied Veterinary Medicine, 7(3), 158–162.

Gavrilin, P. N., Gavrilina, E. G., & Evert, V. V. (2017a). Histoarchitectonics of the parenchyma of lymph nodes of mammals with different structure of intranodal lymphatic channel. Ukrainian Journal of Ecology, 7(3), 96–107.

Gavrilin, P. N., Gavrilina, O. G., Brygadyrenko, V. V., & Rahmoun, D. E. (2017b). Structural and functional units of parenchyma of lymph nodes of dromedaries (Camelus dromedarius). Regulatory Mechanisms in Biosystems, 8(3), 323–332.

Gavrilin, P. N., Lieshchova, M. A., & Rahmoun, D. E. (2015). Features of zonal structure of the parenchyma and intra-site lymphatic channel of lymph node in dromedary. The Animal Biology, 17(3), 29–37.

Gavrilin, P. N., Lieshchova, M. A., Gavrilina, O. G., & Boldyreva, T. F. (2018). Prenatal morphogenesis of compartments of the parenchyma of the lymph nodes of domestic cattle (Bos taurus). Regulatory Mechanisms in Biosystems, 9(1), 95–104.

Gor, D. M., Langer, J. E., & Loevner, L. A. (2006). Imaging of cervical lymph nodes in head and neck cancer: The basics. Radiologic Clinics of North America, 44(1), 101–110.

Gouda, S. (2016). Comparative histomorphology and histochemistry of thoracic aorta in deccani sheep and bidri goat. MOJ Anatomy and Physiology, 2(3), 44.

Harisinghani, M. G. (2012). Pelvic lymph nodes. Atlas of lymph node anatomy, 89–153.

Janvier, V., Evrard, L., Cerri, S., Gougnard, A., & Busoni, V. (2015). Ultrasonographic findings in 13 horses with lymphoma. Veterinary Radiology and Ultrasound, 57(1), 65–74.

Kelch, I. D., Bogle, G., Sands, G. B., Phillips, A. R. J., LeGrice, I. J., & Dunbar, P. R. (2019). High-resolution 3D imaging and topological mapping of the lymph node conduit system. PLoS Biology, 17(12), e3000486.

Kraitchman, D., Kamel, I., Weiss, C., & Georgiades, C. (2017). Elucidation of percutaneously accessible lymph nodes in swine: A large animal model for interventional lymphatic research. Journal of Vascular and Interventional Radiology, 28(3), 451–456.

Lossi, L., D’Angelo, L., De Girolamo, P., & Merighi, A. (2016). Anatomical features for an adequate choice of experimental animal model in biomedicine: II. Small laboratory rodents, rabbit, and pig. Annals of Anatomy – Anatomischer Anzeiger, 204, 11–28.

Maher, M. A., Farghali, H. A. M., Abdelnaby, E. A., & Emam, I. A. (2020). Gross anatomical, radiographic and doppler sonographic approach to the infra-auricular parotid region in donkey (Equus asinus). Journal of Equine Veterinary Science, 88, 102968.

Mallet, C., Cornette, R., & Guadelli, J. (2019). Morphometrical distinction between sheep (Ovis aries) and goat (Capra hircus) using the petrosal bone: Application on french protohistoric sites. International Journal of Osteoarchaeology, 29(4), 525–537.

Margaris, K. N., & Black, R. A. (2012). Modelling the lymphatic system: Challenges and opportunities. Journal of the Royal Society Interface, 9(69), 601–612.

Mebius, R. E. (2003). Organogenesis of lymphoid tissues. Nature Reviews Immunology, 3(4), 292–303.

Nourinezhad, J., Mazaheri, Y., & Biglari, Z. (2015). Detailed anatomy of the cranial cervical ganglion in the dromedary camel (Camelus dromedarius). The Anatomical Record, 298(8), 1479–1491.

Nourinezhad, J., Mazaheri, Y., & Saberifar, S. (2016). Topography and morphology of the bovine cranial cervical ganglion and its branches. International Journal of Morphology, 34(2), 545–556.

Pabst, R. (2020). The pig as a model for immunology research. Cell and Tissue Research, 380(2), 287–304.

Rebelatto, M. C. (2018). Spleen, lymph nodes, and thymus. Boorman’s Pathology of the Rat, 469–491.

Reiter, R., Viehdorfer, M., Hescock, K., Clark, T., & Nemanic, S. (2017). Effectiveness of a radiographic anatomy software application for enhancing learning of veterinary radiographic anatomy. Journal of Veterinary Medical Education, 2017, 1–9.

Saliman, S. M., & Mazher, K. M. (2005). Light and electron microscopic studies on some lymph nodes of the adult one-humped camel (Camelus dromedarius). Beni Suef Veterinary Medicine Journal, 15(2), 9–13.

Stahle, J. A., Larson, M. M., Rossmeisl, J. H., Dervisis, N., & Neelis, D. (2018). Diffusion weighted magnetic resonance imaging is a feasible method for characterizing regional lymph nodes in canine patients with head and neck disease. Veterinary Radiology and Ultrasound, 60(2), 176–183.

Sun, X., Liu, E., Iqbal, A., Wang, T., Wang, X., Haseeb, A., Ahmed, N., Yang, P., & Chen, Q. (2019). The dynamic distribution of duck Tembusu virus in the spleen of infected shelducks. BMC Veterinary Research, 15, 1.

Taher, E.-S. M., El-Sakhawy, M. A., Moussalam, E.-S., Moussa, M. H. G., & El-Bargeesy, G. (1989). Studies of the lymphoid tissue of lymph nodes of one humped camel fetuses (Camelus dromedarius). Egypt Journal Histology, 12(1), 23–33.

Watson, E., & Heng, H. G. (2017). Forensic radiology and imaging for veterinary radiologists. Veterinary Radiology and Ultrasound, 58(3), 245–258.

Willard-Mack, C. L. (2006). Normal structure, function, and histology of lymph nodes. Toxicologic Pathology, 34(5), 409–424.

Ying, M., & Ahuja, A. (2003). Sonography of neck lymph nodes. Part I: Normal lymph nodes. Clinical Radiology, 58(5), 351–358.

Zidan, M., & Pabst, R. (2002). Detection of apoptosis in the lymphoid organs of the dromedary camel. Journal of Camel Practice and Research, 9(2), 163–166.

Zidan, M., & Pabst, R. (2012). Histological, histochemical and immunohistochemical study of the lymph nodes of the one humped camel (Camelus dromedarius). Veterinary Immunology and Immunopathology, 145(1–2), 191–198.

How to Cite
Rahmoun, D. E., Lieshchova, M. A., & Fares, M. A. (2020). Morphological and radiological study of lymph nodes in dromedaries in Algeria . Regulatory Mechanisms in Biosystems, 11(2), 330-337.

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