Evaluation of levels of bradykinin, intercellular adhesion molecule-ICAM and electrolytes in patients with ischemic stroke
Abstract
Stroke is one of the leading causes of death worldwide, especially among the elderly. Fifty blood samples were collected from patients (25 females and 25 males) suffering from ischemic stroke (IS) who visited the central health laboratories at the Medical City. The p atients belonged to different age groups ranging from 45 – 65 years. Twenty samples (10 females and 10 males) were collected from healthy individuals who did not suffer from any diseases as a control group. Several biochemical parameters were tested, such as intercellular adhesion molecule ( ICAM ) , bradykinin , sodium and potassium in the patient’s blood serum. The results of the present study indicated a significant elevat ion in ICAM, bradykinin , Na, K in the blood serum of the patient group compared to the control group. The results also showed a highly significant positive correlation between bradykinin concentration and ICAM in the blood serum of the patient group, as the value of the correlation coefficient was 0.724. The results also showed that the area under the curve value for the studied variables, ICAM, bradykinin, was excellent, so they can be cons i dered important diagnostic variables for patients with ischemic stroke.References
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