Effects of melatonin on cognitive processes and astroglia state in rats with experimental diabetes

  • N. V. Nedzvetskaya Оles’ Gonchar Dnipropetrovsk National University
  • N. I. Таshevskaya Dnipropetrovsk State Medical Academy

Abstract

There was investigated protective effect of chronic melatonin injection on the development of cognitive deficit in rats with streptozotocine induced diabetes. There were observed decrease of astrogliosis and of cognitive deficit in animals that were injected with melatonin. Presented results are evidence that melatonin can prevent the development of cognitive deficit in diabetic animals by decreasing oxidative stress level and astrogliosis inhibition.

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Published
2010-07-04
How to Cite
Nedzvetskaya, N. V., & ТаshevskayaN. I. (2010). Effects of melatonin on cognitive processes and astroglia state in rats with experimental diabetes. Regulatory Mechanisms in Biosystems, 1(1), 97-102. https://doi.org/10.15421/021016