Compositions of essential oils with antimicrobial properties against isolates from oral cavities of patients with inflammatory diseases of the periodontium


Keywords: antibiotic resistant isolates; opportunistic pathogenic microorganisms; аntibacterial activity; anti-mycotic effect

Abstract

The significant spread of antibiotic-resistant microorganisms which are part of microbial associations of the oral cavity is considered one of the main causes for the complications and relapses of inflammatory diseases of the periodontium. This problem underlines the importance of constant monitoring of the circulation of polyantibiotic-resistant isolates, and development of new approaches and means of correction for the microbiocoenosis of the oral cavity affected by inflammatory processes. The paper is dedicated to research of antimicrobial properties of essential oil compositions against opportunistic pathogenic microorganisms, agents of inflammatory diseases of the periodontium. Out of the microorganisms isolated from the nidus of inflammation, the extra antibiotic-resistant ones were chosen. For the purpose of antibiotic susceptibility and antimicrobial activity testing, the disc diffusion method was used. The following compositions were manufactured from essential oils: Hyssopus officinalis L. + Rossmarinus officinalis L.; Menta piperita L. + H. officinalis; R. officinalis + Coriandrum sativum L.; R. officinalis + M. piperita + H. officinalis. The compositions H. officinalis + R. officinalis; M. piperita + H. officinalis were shown to have the highest level of antibacterial activity against clinical and typical isolates. Combinations of essential oils demonstrated a broader spectrum of activity against microorganisms than their components taken separately. Certain essential oils and the compositions H. officinalis + R. officinalis; M. piperita + H. officinalis were ascertained to have a high anti-mycotic activity against Candida genus microscopic fungi. This fact proves the advantage of application of combinations of essential oils compared to the use of their separate components. However, not all variants reviewed showed additive antimicrobial effect of the use of combinations of essential oils. The compositions that showed high antibacterial properties against the reviewed isolates may be used for oral hygiene products.

References

Assaf, A. M., Amro, B. I., Mashallah, S., & Haddadin, R. N. (2016). Antimicrobial and anti-inflammatory potential therapy for opportunistic microorganisms. The Journal of Infection in Developing Countries, 10(5), 494.


Balouiri, M., Sadiki, M., & Ibnsouda, S. K. (2016). Methods for in vitro evaluating antimicrobial activity: A review. Journal of Pharmaceutical Analysis, 6(2), 71–79.


Bassolé, I. H. N., & Juliani, H. R. (2012). Essential oils in combination and their antimicrobial properties. Molecules, 17(4), 3989–4006.


Bueno, J., Demirci, F., & Husnu Can Baser, K. (Eds.). (2017). 6: Essential oils against microbial resistance mechanisms, challenges and applications in drug discovery. Essential oils and nanotechnology for treatment of microbial diseases. Pp. 143–158.


Celikel, N., & Kavas, G. (2008). Antimicrobial properties of some essential oils against some pathogenic microorganisms. Czech Journal of Food Sciences, 26(3), 174–181.


Fu, Y., Zu, Y., Chen, L., Shi, X., Wang, Z., Sun, S., & Efferth, T. (2007). Antimicrobial activity of clove and rosemary essential oils alone and in combination. Phytotherapy Research, 21(10), 989–994.


Größner-Schreiber, B., Teichmann, J., Hannig, M., Dörfer, C., Wenderoth, D. F., & Ott, S. J. (2009). Modified implant surfaces show different biofilm compositions underin vivoconditions. Clinical Oral Implants Research, 20(8), 817–826.


Harris, B. (2002). The antimicrobial properties of essential oils. International Journal of Aromatherapy, 12(2), 113.


Jakobi, M., Stumpp, S., Stiesch, M., Eberhard, J., & Heuer, W. (2015). The peri-implant and periodontal microbiota in patients with and without clinical signs of inflammation. Dentistry Journal, 3(2), 24–42.


Kalemba, D., & Kunicka, A. (2003). Antibacterial and antifungal properties of essential oils. Current Medicinal Chemistry, 10(10), 813–829.


Koba, K., Nénonéné, A. Y., Sanda, K., Garde, D., Millet, J., Chaumont, J.-P., & Raynaud, C. (2011). Antibacterial activities of coleus aromaticus benth (Lamiaceae) essential oil against oral pathogens. Journal of Essential Oil Research, 23(1), 13–17.


Kryvtsova, M. V., Kohuch, T. T., Salamon, I., Spivak, M. J. (2018). Antimicrobial activity of some essential oils on Candida genus clinical isolates. Mikrobiolohichnyi Zhurnal, 80(4), 3–12.


Kryvtsova, M., Rivis, O., Babenko, L., Spivak, N., Nikolaichuk, V., Ganic, T. (2017). Antibacterial properties of essential oils against specific opportunistic pathogenic bacteria. Proceedings of 2nd Japan Turkey International Symposium on Pharmaceutical and Biomedical Sciences (JATUSPAB-2), Trabzon. Pp. 30.


Marino, M., Bersani, C., & Comi, G. (1999). Antimicrobial activity of the essential oils of Thymus vulgaris L. measured using a bioimpedometric method. Journal of Food Protection, 62(9), 1017–1023.


Millezi, A. F., Caixeta, D. S., Rossoni, D. F., Cardoso, M. das G., & Piccoli, R. H. (2012). In vitro antimicrobial properties of plant essential oils Thymus vulgaris, cymbopogon citratus and laurus nobilis against five important foodborne pathogens. Food Science and Technology, 32(1), 167–172.


Mohamed, S. B., & Eddine, A. D. (2010). Antibacterial activity of essential oils of some Algerian aromatic plants against multidrug resistant bacteria. Journal of Essential Oil Bearing Plants, 13(3), 362–370.


Murbach Teles Andrade, B. F., Nunes Barbosa, L., da Silva Probst, I., & Fernandes Júnior, A. (2013). Antimicrobial activity of essential oils. Journal of Essential Oil Research, 26(1), 34–40.


Newman, D. J., & Cragg, G. M. (2007). Natural products as sources of new drugs over the last 25 years. Journal of Natural Products, 70(3), 461–477.


Rhos, J. L., & Recio, M. C. (2005). Medicinal plants and antimicrobial activity. Journal of Ethnopharmacology, 10(1–2), 80–84.


Salamon, I., Ibraliu, A., & Kryvtsova, M. (2017). Essential oil of common juniper (Jiniperus communis L.) in Albania. Scientific Bulletin of the Uzhhorod University, Series Biology, 42, 72–75.


Schindel, L. (2013). Antibiotic-resistant bacteria. Unexpected Reactions to Modern Therapeutics, 94–101.


Semeniuc, C. A., Pop, C. R., & Rotar, A. M. (2017). Antibacterial activity and interactions of plant essential oil combinations against Gram-positive and Gram-negative bacteria. Journal of Food and Drug Analysis, 25(2), 403–408.


Sujana, P., Sridhar, T. M., Josthna, P., & Naidu, C. V. (2013). Antibacterial activity and phytochemical analysis of Mentha piperita L. (Pepper mint) an important multipurpose medicinal plant. American Journal of Plant Sciences, 4(1), 77–83.


Tada, A., Senpuku, H., Motozawa, Y., Yoshihara, A., Hanada, N., & Tanzawa, H. (2006). Association between commensal bacteria and opportunistic pathogens in the dental plaque of elderly individuals. Clinical Microbiology and Infection, 12(8), 776–781.

Published
2018-10-21
How to Cite
Kryvtsova, M. V., Kostenko, Y. Y., & Salamon, I. (2018). Compositions of essential oils with antimicrobial properties against isolates from oral cavities of patients with inflammatory diseases of the periodontium. Regulatory Mechanisms in Biosystems, 9(4), 491-494. https://doi.org/https://doi.org/10.15421/021873

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