Effects of IGF2 genotypes on growth performance and meat productivity of three-way hybrid pigs

  • O. M. Tsereniuk Institute of Pig Breeding and Agroindustrial Production of National Academy of Agrarian Sciences of Ukraine
  • A. M. Saienko Institute of Pig Breeding and Agroindustrial Production of National Academy of Agrarian Sciences of Ukraine
  • I. O. Buhai Institute of Pig Breeding and Agroindustrial Production of National Academy of Agrarian Sciences of Ukraine
  • V. O. Skrypnyk Institute of Pig Breeding and Agroindustrial Production of National Academy of Agrarian Sciences of Ukraine
  • I. O. Pchelnik Poltava State Agrarian University
  • O. G. Fesenko Poltava State Agrarian University
  • B. S. Shaferivskyi Poltava State Agrarian University
  • P. А. Vashchenko Poltava State Agrarian University
DOI: https://doi.org/10.15421/0226084
Keywords: marker-assisted selection, insulin-like growth factor 2, Danish pig breeds, backfat thickness, average daily gain, economic efficiency, genetic diversity.

Abstract

The study investigated the association between IGF2 gene polymorphism and productive traits of commercial hybrid pigs obtained by crossing Danish Large White and Landrace sows with Duroc and Pietrain boars. The objective of the research was to evaluate the influence of IGF2 genotypes on fattening, carcass, meat productivity, and economic efficiency traits in modern commercial crossbreeding combinations. Genotyping was performed using PCR-RFLP analysis. Four hybrid combinations were studied: LWxLxD, LxLWxD, LWxLxP, and LxLWxP. Allele and genotype frequencies, Hardy–Weinberg equilibrium parameters, productive performance, carcass characteristics, and economic indicators were analyzed. The results demonstrated moderate heterozygosity (He = 0.42–0.492) and the absence of significant deviations from Hardy–Weinberg equilibrium in all experimental groups, indicating stability of the genetic structure at the IGF2 locus. Animals carrying AA and AB genotypes generally showed higher average daily gain, greater absolute weight gain, and shorter fattening periods compared with BB genotype carriers. Significant differences were observed for average daily gain, age at reaching 100 kg body weight, feed consumption, and absolute gain. The influence of the IGF2 polymorphism on carcass and meat traits was also established, particularly for preslaughter weight, transport weight, carcass length measured from the first cervical vertebra, carcass length measured from the first rib, and backfat thickness. In most cases, AA and AB genotypes were associated with better growth intensity and improved carcass quality, whereas BB animals tended to have thicker backfat. Economic evaluation showed that pigs with the AA genotype had the lowest production cost, the highest profitability level, and the greatest net profit per animal. The obtained results confirm the practical significance of the IGF2 locus as a promising marker for marker-assisted selection aimed at improving growth pe r formance, meat productivity, and economic efficiency in commercial pig production systems.

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Published
2026-05-24
How to Cite
Tsereniuk, O. M., Saienko, A. M., Buhai, I. O., Skrypnyk, V. O., Pchelnik, I. O., Fesenko, O. G., Shaferivskyi, B. S., & VashchenkoP. А. (2026). Effects of IGF2 genotypes on growth performance and meat productivity of three-way hybrid pigs. Regulatory Mechanisms in Biosystems, 17(4), e26084. https://doi.org/10.15421/0226084
Issue
Vol 17 No 4 (2026): Regulatory Mechanisms in Biosystems
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