Assessment of administration pattern of laxatives in pharmacies in Nasiriya City, Iraq
Abstract
Constipation affects 15–20% of the global population and is classified as primary or secondary. Primary constipation involves neuromuscular or sensory dysfunction, while secondary causes include medications, metabolic disorders, or structural abnormalities. The objective of this study was to determine the laxatives most frequently dispensed by the community pharmacists in Nasiriyah city, Southern Iraq. The data included information on dosage forms, dose, frequency, interval between doses, safety in pregnancy and lactation, and adverse reactions. The research took place during 10 months (from January to October 2023). Bisacodyl was found to be the most widely prescribed laxative (48.7%) in Nasiriyah, followed by lactulose (25.0%). Oral forms were preferred (81.2%). Safety was the primary decision factor (35.0%) and efficacy and cost as well had significant roles. W e found that bisacodyl is more popular in Nasiriyah than U.S. or Europe , where lactulose is mo re frequently used . This indicates that differences in the medical practice, recommendations, and availability of drugs themselves impact regional prescribing . In Southern Iraq, bisacodyl remains dominant, with minor variations among governorates. These findings highlight the need for localized research to understand and improve healthcare practices. Given the variety of laxatives and their impact on safety and efficacy, assessing their usage is crucial. Our findings recommend aligning laxative prescription practices with WHO guid e lines. We also suggest implementing a stricter follow-up system for over-the-counter sales in Iraqi pharmacies to ensure proper use and reduce risks from misuse. This is vital for improving public health.References
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